The guest lectures are one of the main highlights of the activities of E-Cell in its quest of inculcating the spirit of entrepreneurship among the students. The lectures aim to provide an insight into the success stories of top-notch entrepreneurs. Students get the opportunity to know about the real world experiences of their role models. Big-shot entrepreneurs and corporate leaders have delivered their inspiring lectures to the students in the past.

Some of the past speakers were:

• Dr. K. C. Chakrabarty- Deputy Governor of the Reserve Bank of India,and former CMD of PNB BANK
• Dominique Trempont – On the Board of Directors of three multinational companies {3com,Finisar and Energy Recovery Inc}.Worked with Steve Jobs as the CFO of NeXT
• Sramana Mitra – US-based Strategy Consultant and Forbes Columnist
• Mr. Anand Sen -VP Flat Products , Tata Steel
• Sunil Handa – Serial Entrepreneur and Visiting Faculty at IIM Ahemdabad
• Sanjeev Bhikchandani – CEO of Naukri.com
• Arjun Malhotra – Co founder, HCL technologies with Mr. Shiv Nadar. Currently the CEO of Headstrong; a US based IT consulting company.
• Vinod Dham - Popularly known as the father of the Pentium processor. Presently, he is the chairman, president and chief executive officer of Silicon Spice, a communications technology development firm.
• Rashmi Bansal - The author of bestseller ‘Stay Hungry Stay Foolish’, Rashmi Bansal is a writer, an entrepreneur and a youth expert. In a country where selling 10,000 copies is considered a ‘bestseller’, 100,000 copies of the book have been sold in just 9 months of its release.
• Mr. Vasant Subramanyan - President, TiE Kolkata and Director and CEO "Last Speak Group".
• Mr. Rajdeep Sehrawat - Vice President, NASSCOM